@import url('https://fonts.googleapis.com/css2?family=Manrope:wght@400;500;550;600;650;700&display=swap');
:root{font-family:Manrope,-apple-system,BlinkMacSystemFont,"Segoe UI",sans-serif;color:#efedf2;background:#0c0c0f;color-scheme:dark;--muted:#a39da9;--accent:#ceb5e6;--line:#ffffff13;font-synthesis:none}*{box-sizing:border-box}body{margin:0}a{color:inherit;text-decoration:none}button,input,select{font:inherit;color:inherit}button,a,select,input,summary{touch-action:manipulation}button{cursor:pointer;background:none;border:0}button:disabled{opacity:.35;cursor:default}button:focus-visible,a:focus-visible,select:focus-visible,input:focus-visible,summary:focus-visible{outline:2px solid var(--accent);outline-offset:5px}::selection{background:#604777;color:white}[hidden]{display:none!important}.sr-only{position:absolute;clip:rect(0,0,0,0);width:1px;height:1px;overflow:hidden;white-space:nowrap}.skip{position:fixed;top:-60px;left:20px;background:white;color:black;z-index:200;padding:12px}.skip:focus{top:12px}summary{cursor:pointer;list-style:none}summary::-webkit-details-marker{display:none}.topbar{height:96px;max-width:1440px;margin:auto;padding:0 5%;display:flex;align-items:center;justify-content:space-between;gap:28px;border-bottom:1px solid var(--line)}.brand{display:flex;align-items:center;gap:22px}.brand svg{width:135px;height:auto}.brand>span{font-size:11px;letter-spacing:.18em;color:#a899b5;border-left:1px solid #ffffff22;padding-left:22px}.topbar nav{display:flex;align-items:center;gap:36px;font-size:14px;color:var(--muted)}.topbar nav a{padding:15px 0}.topbar nav a:hover,.topbar nav a[aria-current]{color:white}.icon-button{width:44px;height:44px;display:flex;align-items:center;justify-content:center;font-size:28px}.menu-toggle{flex-direction:column;gap:7px;align-items:flex-end}.menu-toggle span{width:25px;height:1px;background:#d8d2de}.menu-toggle span:last-child{width:18px}main{max-width:1120px;margin:auto;padding:76px 40px 96px}.page-heading{margin-bottom:62px}.eyebrow{font-size:11px;font-weight:600;letter-spacing:.2em;color:#aa91bd;margin:0 0 21px}.page-heading h1{font-size:clamp(34px,4.2vw,52px);font-weight:500;letter-spacing:-.055em;line-height:1.15;margin:0 0 20px}.intro{font-size:17px;color:#a59daa;line-height:1.7;margin:0}.workspace{width:100%}.compound-content{min-width:0}.profile-row{display:flex;align-items:center;justify-content:space-between;gap:24px;margin-bottom:30px}.profile-category{font-size:12px;color:#9c8ca8;margin:0 0 12px;letter-spacing:.025em}.profile-head h2{font-size:34px;font-weight:500;letter-spacing:-.04em;line-height:1.2;margin:0}.choose-button{display:flex;align-items:center;gap:22px;font-size:14px;padding:13px 18px;border:1px solid #ffffff25;border-radius:100px;color:#dbd1e4;min-height:46px;white-space:nowrap}.choose-button:hover{border-color:#ad90c1;background:#ffffff04}.choose-button span{font-size:18px;color:var(--accent)}.identity-note{border-left:1px solid #9b8968;padding:3px 0 3px 15px;font-size:13px;color:#b7a689;margin-bottom:25px}.identity-note summary{padding:4px 0}.identity-note p{max-width:700px;font-size:14px;line-height:1.8;color:#baafbe;margin:12px 0 8px}.tabbar{display:flex;gap:36px;border-bottom:1px solid var(--line);margin-bottom:38px}.tabbar button{padding:17px 0 18px;margin-bottom:-1px;border-bottom:2px solid transparent;font-size:15px;color:#98909f;display:flex;align-items:center;gap:13px}.tabbar button[aria-selected=true]{border-color:var(--accent);color:#f2e9fa}.tabbar button span{color:#a58ab9;font-size:16px}#library-panel{max-width:900px}.search-box{display:flex;align-items:center;gap:14px;min-width:0;padding:0 16px;border:1px solid #ffffff22;border-radius:10px;background:#ffffff03}.search-box:focus-within{border-color:#9277a5}.search-box svg{fill:none;stroke:#a595b1;stroke-width:1.5;width:20px;height:20px;flex-shrink:0}.search-box input{width:100%;min-width:0;border:0;outline:0;background:transparent;padding:17px 0;font-size:16px}.search-box input::placeholder{color:#8e8398}.paper-search{padding:7px 8px 7px 17px}.paper-search input{padding:11px 0}.action-button{padding:12px 23px;border-radius:7px;background:#dfd3e9;color:#201a27;font-size:14px;font-weight:600}.action-button:hover{background:#efe4f8}.filter-drawer{margin:16px 0 36px}.filter-drawer>summary{display:flex;align-items:center;gap:9px;width:max-content;min-height:40px;padding:7px 0;color:#b8a9c4;font-size:14px}.disclosure-icon{font-size:20px;font-weight:400;color:#9b85ab;line-height:1;display:inline-block;transition:transform .2s}details[open]>summary>.disclosure-icon{transform:rotate(45deg)}#filter-count:not(:empty){font-size:11px;border-radius:100px;min-width:18px;text-align:center;padding:2px 5px;background:#493753;color:#ecdef6}.paper-filters{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:22px 20px;padding:22px 24px;margin-top:6px;border:1px solid var(--line);border-radius:10px;background:#121016}.paper-filters>label:not(.oa-label){display:flex;flex-direction:column;gap:10px;font-size:12px;color:#a094aa}select{font-size:14px;border:1px solid #ffffff1b;border-radius:6px;background:#1a161f;padding:11px 24px 11px 11px;min-width:0;max-width:100%}.oa-label{display:flex;align-items:center;gap:9px;grid-column:span 2;font-size:14px;color:#c4b9cd}.oa-label input{width:17px;height:17px;accent-color:#bda2d4}.reset-button{justify-self:end;font-size:13px;color:var(--accent);padding:9px 0}.results-heading{display:flex;justify-content:space-between;align-items:center;gap:20px;margin-bottom:10px}.results-heading h3{font-size:14px;color:#c0b3cc;font-weight:500;margin:0}.sort-label{display:flex;align-items:center;gap:6px;font-size:12px;color:#8a7e95}.sort-label select{border:0;background:none;padding:8px;font-size:12px;color:#b6a5c4}.results-status{font-size:12px;line-height:1.7;color:#8b7b98;min-height:20px;margin-bottom:13px;max-width:700px}.results-status button{color:var(--accent);text-decoration:underline;padding:0 4px}.paper-card{padding:32px 0 34px;border-top:1px solid var(--line)}.paper-meta{display:flex;align-items:center;flex-wrap:wrap;gap:15px;font-size:12px;color:#9c8da9;margin-bottom:16px}.paper-meta .year{color:#c1b08f}.oa-tag{color:#b6a1c5}.paper-card h4{font-size:21px;font-weight:500;line-height:1.55;letter-spacing:-.02em;max-width:800px;margin:0 0 13px}.paper-card h4 a:hover{color:var(--accent)}.paper-journal{font-size:14px;line-height:1.7;color:#9c90a7;margin:0;max-width:720px}.paper-bottom{display:flex;align-items:flex-start;gap:30px;margin-top:22px;flex-wrap:wrap}.read-source{font-size:14px;color:var(--accent);padding-top:2px;white-space:nowrap}.read-source:hover{text-decoration:underline}.paper-details{flex:1;min-width:130px}.paper-details>summary{font-size:13px;color:#9583a4;padding:3px 0}.paper-details>summary span{margin-left:7px}.paper-detail-body{padding-top:16px;font-size:12px;color:#9e8baa;line-height:1.8}.paper-detail-body p{margin:0 0 14px;font-size:13px;line-height:1.8;overflow-wrap:anywhere}.paper-links{display:flex;flex-wrap:wrap;gap:20px;margin-top:16px;color:#cbb3de;font-size:13px}.load-more{display:block;margin:25px auto 10px;padding:13px 26px;font-size:14px;border:1px solid #725987;border-radius:100px;color:#d1b6e4}.source-footer{display:flex;justify-content:space-between;align-items:baseline;gap:25px;border-top:1px solid var(--line);padding-top:28px;margin-top:20px;color:#87788f}.source-footer p{font-size:12px;line-height:1.8;margin:0;max-width:470px}.source-footer a{font-size:13px;color:#b6a0c9;white-space:nowrap}.empty-state{text-align:center;padding:70px 25px;border-top:1px solid var(--line);color:#a391b0}.empty-state h4{font-weight:500;font-size:22px;color:#dcd0e6;margin:0 0 18px}.empty-state p{max-width:430px;font-size:15px;line-height:1.9;margin:0 auto 23px}.empty-state a{font-size:14px;color:var(--accent)}.explorer-layout{border:1px solid var(--line);border-radius:16px;overflow:hidden;background:#100e16}.viewer-top{display:flex;justify-content:space-between;align-items:center;gap:20px;padding:20px 24px;color:#b09bc1;font-size:11px;letter-spacing:.12em}.viewer-top select{font-size:12px;background:#1c1623;border-color:#ffffff18;padding:8px 12px;letter-spacing:0}.viewer-stage{position:relative;height:460px;isolation:isolate}#molecule-viewer{position:absolute;inset:0}.viewer-message{position:absolute;inset:0;padding:40px;display:flex;align-items:center;justify-content:center;flex-direction:column;text-align:center;font-size:15px;line-height:1.9;color:#a897b5;background:#100e16}.viewer-message strong{font-size:25px;font-weight:500;letter-spacing:-.025em;margin-bottom:17px;color:#e3d3ed}.viewer-message span{max-width:420px}.viewer-controls{position:absolute;bottom:13px;left:0;right:0;display:flex;justify-content:center;gap:7px;pointer-events:none}.viewer-controls button{pointer-events:auto;background:#211a2aec;border:1px solid #ffffff19;border-radius:100px;min-width:42px;min-height:42px;padding:9px 17px;font-size:13px;backdrop-filter:blur(10px)}.viewer-controls button[aria-pressed=true]{background:#4d395f;border-color:#9274a9}.viewer-caption{display:flex;justify-content:space-between;flex-wrap:wrap;gap:20px;padding:21px 24px;font-size:12px;line-height:1.7;color:#a18cad}.element-key{display:flex;align-items:center;gap:6px;font-size:11px}.element-key i{display:inline-block;width:6px;height:6px;border-radius:50%;margin-left:9px}.carbon{background:#bbb}.nitrogen{background:#4265ed}.oxygen{background:#ec4545}.sulfur{background:#e5ce30}.sequence-panel{display:grid;grid-template-columns:180px 1fr;gap:8px 24px;align-items:center;padding:30px 0}.sequence-panel h3{font-size:14px;color:#ae9cbb;font-weight:500;margin:0}#sequence-buttons{display:flex;gap:7px;flex-wrap:wrap}#sequence-buttons button{display:flex;flex-direction:column;align-items:center;gap:7px;min-width:40px;padding:10px;border:1px solid #ffffff12;border-radius:7px;font-family:monospace;font-size:17px;color:#cbb2df;background:#19131e}#sequence-buttons button small{font-size:10px;color:#8e799e}#sequence-buttons button[aria-pressed=true]{background:#5e4377;color:#fff;border-color:#a684bc}#residue-details{grid-column:2;font-size:12px;line-height:1.7;color:#9680a5;margin:7px 0 0}.selection-info{margin:0 0 30px;padding:23px 26px;border-left:2px solid #9371aa;background:#ffffff02;max-width:740px}.selection-info h4{font-size:16px;font-weight:500;color:#dfcbeD;margin:0 0 12px}.selection-info p{font-size:14px;line-height:1.8;color:#b1a0bd;margin:7px 0}.selection-info h4 span{color:#9c82ae}.structure-details{border-top:1px solid var(--line);border-bottom:1px solid var(--line);margin-top:12px}.structure-details>summary{display:flex;align-items:center;justify-content:space-between;padding:23px 0;font-size:14px;color:#b7a8c2}.structure-details dl{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:24px;margin:8px 0 25px}.structure-details dt{font-size:12px;color:#93819f;margin-bottom:10px}.structure-details dd{font-size:16px;margin:0;overflow-wrap:anywhere;color:#dfd0ea}.structure-details dd small{font-size:12px;color:#a691b5}.structure-note{font-size:14px;line-height:1.85;color:#a491b3;max-width:730px;margin:20px 0}.source-link{display:inline-block;color:var(--accent);font-size:13px;margin:0 0 25px}.explorer-bottom{padding-top:25px}.explorer-bottom button{font-size:14px;padding:10px 0;color:var(--accent)}footer{max-width:1360px;margin:auto;padding:32px 5% 40px;display:flex;align-items:center;justify-content:space-between;gap:24px;border-top:1px solid var(--line);color:#80718c;font-size:12px}footer>a{font-size:14px;font-weight:650;letter-spacing:.13em;color:#c9bdd4}footer span:nth-child(2){color:#a78fba}dialog{color:#ece5f2;background:#121017;border:1px solid #ffffff1b}dialog::backdrop{background:#050407b8;backdrop-filter:blur(12px)}#compound-dialog{width:min(520px,calc(100% - 32px));max-height:85dvh;border-radius:16px;padding:25px 28px 20px;overflow:auto}#compound-dialog[open]{animation:picker-in .2s ease-out}.picker-head{display:flex;align-items:center;justify-content:space-between;gap:16px;margin-bottom:22px}.picker-head h2{font-size:22px;font-weight:500;letter-spacing:-.03em;margin:0}.picker-head h2 span{font-size:12px;color:#ac94bd;margin-left:8px}#compound-dialog .search-box{background:#1b1522}.category-label{display:block;font-size:12px;color:#9883a7;margin:20px 0 9px}#category{width:100%}.list-count{font-size:12px;color:#87728f;margin:22px 0 12px}#compound-list{max-height:42dvh;overflow:auto;scrollbar-width:thin;scrollbar-color:#4b365c transparent}#compound-list a{display:flex;align-items:center;justify-content:space-between;gap:14px;padding:15px 13px;font-size:15px;border-radius:7px;margin-bottom:3px;color:#bbadc7}#compound-list a:hover,#compound-list a[aria-current]{background:#2b2036;color:#eee1f9}#compound-list a span{color:#b797d0;opacity:0}#compound-list a[aria-current] span{opacity:1}#menu{inset:0 0 0 auto;margin:0;width:min(430px,92%);height:100dvh;max-height:none;max-width:none;border-width:0 0 0 1px;padding:35px 30px;overflow:auto}#menu[open]{animation:slide-in .4s cubic-bezier(.22,1,.36,1)}#menu.closing{animation:slide-out .28s ease-in}.menu-head{display:flex;align-items:center;justify-content:space-between;font-size:20px;font-weight:650;letter-spacing:.06em}#menu nav{display:flex;flex-direction:column;margin:70px 0}#menu nav a{display:flex;align-items:center;gap:16px;font-size:23px;letter-spacing:-.03em;padding:24px 0;border-bottom:1px solid var(--line)}#menu nav a span{font-size:11px;color:#9e7ebc}#menu>p{font-size:12px;letter-spacing:.18em;text-transform:uppercase;color:var(--accent)}.loading{font-size:14px;line-height:1.7;color:#b199c3;padding:20px}.noscript{text-align:center;padding:35px}@keyframes picker-in{from{opacity:0;transform:translateY(8px)}to{opacity:1;transform:translateY(0)}}@keyframes slide-in{from{transform:translateX(100%)}to{transform:translateX(0)}}@keyframes slide-out{to{transform:translateX(100%)}}
@media(max-width:1000px){.topbar nav{gap:24px}.brand>span{display:none}main{padding:60px 40px 70px}.page-heading{margin-bottom:50px}.viewer-stage{height:400px}.structure-details dl{grid-template-columns:repeat(2,minmax(0,1fr))}}
@media(max-width:650px){.topbar{height:78px;padding:0 24px}.topbar nav{display:none}.brand svg{width:123px}.brand>span{display:block;font-size:10px;padding-left:15px}.brand{gap:15px}main{padding:42px 24px 60px}.page-heading{margin-bottom:42px}.page-heading .eyebrow{font-size:10px;margin-bottom:18px}.page-heading h1{font-size:34px;margin-bottom:15px;letter-spacing:-.045em}.intro{font-size:15px;line-height:1.8}.profile-row{gap:15px;margin-bottom:21px}.profile-head h2{font-size:28px;overflow-wrap:anywhere}.profile-category{font-size:11px;margin-bottom:11px}.choose-button{font-size:12px;gap:8px;min-height:43px;padding:11px 13px}.choose-button span{font-size:16px}.tabbar{gap:26px;margin-bottom:29px}.tabbar button{font-size:14px;padding:17px 0;gap:9px}.tabbar button span{font-size:14px}.identity-note{font-size:12px}.identity-note p{font-size:13px}.search-box{gap:10px}.search-box svg{width:17px;height:17px}.paper-search{padding:6px 6px 6px 12px}.paper-search input{font-size:14px;padding:12px 0}.action-button{padding:12px 14px;font-size:13px}.filter-drawer{margin:13px 0 24px}.filter-drawer>summary{font-size:13px}.paper-filters{grid-template-columns:1fr 1fr;padding:20px 15px;gap:20px 12px}.paper-filters>label:not(.oa-label){font-size:11px;gap:9px}.paper-filters select{font-size:12px;width:100%;padding:11px 8px}.oa-label{grid-column:auto;align-self:end;min-height:38px;font-size:12px;line-height:1.6}.reset-button{grid-column:2;font-size:12px}.results-heading h3{font-size:13px}.results-status{font-size:11px;line-height:1.8}.sort-label{font-size:11px}.sort-label select{font-size:11px;padding:8px 3px}.paper-card{padding:28px 0 30px}.paper-meta{font-size:11px;gap:12px;margin-bottom:15px}.paper-card h4{font-size:19px;line-height:1.6}.paper-journal{font-size:13px;line-height:1.8}.paper-bottom{gap:24px;margin-top:20px}.read-source{font-size:13px}.paper-details>summary{font-size:12px}.paper-details{min-width:90px}.paper-detail-body p{font-size:12px}.source-footer{flex-direction:column;gap:17px;margin-top:10px}.source-footer p{font-size:11px}.source-footer a{font-size:12px}.viewer-top{padding:16px 14px;font-size:10px;letter-spacing:.06em;gap:8px}.viewer-top select{font-size:11px;padding:8px;max-width:115px}.viewer-stage{height:330px}.viewer-controls{gap:5px}.viewer-controls button{min-width:40px;min-height:40px;padding:9px 14px;font-size:12px}.viewer-caption{padding:18px 16px;gap:14px;font-size:11px}.viewer-message{padding:26px;font-size:14px}.viewer-message strong{font-size:21px}.sequence-panel{grid-template-columns:1fr;gap:17px;padding:27px 0}.sequence-panel h3{font-size:13px}#residue-details{grid-column:1;font-size:11px;margin:0}#sequence-buttons{gap:6px}#sequence-buttons button{min-width:37px;font-size:16px}.selection-info{padding:19px 20px;margin-bottom:24px}.selection-info h4{font-size:15px}.selection-info p{font-size:13px}.structure-details>summary{font-size:13px;padding:22px 0}.structure-details dl{gap:24px 18px}.structure-details dt{font-size:11px}.structure-details dd{font-size:14px}.structure-note{font-size:13px}.source-link{font-size:12px}.explorer-bottom button{font-size:13px}footer{padding:28px 24px 32px;flex-wrap:wrap;font-size:11px;gap:20px}footer span:last-child{width:100%;font-size:10px}#compound-dialog{padding:22px 20px 18px;max-height:88dvh}.picker-head h2{font-size:21px}#compound-dialog .search-box input{font-size:16px}#compound-list a{font-size:14px}.empty-state{padding:55px 10px}.empty-state h4{font-size:20px}.empty-state p{font-size:14px}}
@media(prefers-reduced-motion:reduce){*,*::before,*::after{animation:none!important;transition:none!important}}

.explorer-active main{padding-top:40px}.explorer-active .page-heading{margin-bottom:30px}.explorer-active .page-heading h1{font-size:30px;margin-bottom:0}.explorer-active .page-heading .eyebrow,.explorer-active .page-heading .intro{display:none}.explorer-active .viewer-stage{height:clamp(280px,44vh,460px)}
@media(max-width:650px){.explorer-active main{padding-top:32px}.explorer-active .page-heading{margin-bottom:28px}.explorer-active .page-heading h1{font-size:27px}.explorer-active .viewer-stage{height:330px}}